Over a thousand years ago, a group of people, who were deemed masters in combat of each element, were brought together to defend the continent of Adus. One day an evil was created that almost destroyed the continent and the entire world. The Masters sacrificed themselves and their souls locked in orbs. the orbs were spread out over time. A special type of human, called a cast, was created to stop this evil when it returned. 

Years after the events of RE: The New Cast, The Allied Government of all six nations after looking to have a new position in their government called the Sovereign. A secret group of assassins is making sure one of the candidates wins the coming election. Spex must team up with Revolver to learn why, on top of dealing with a personal issue.